15.02.2009

One year IµS with a mardtb in Basel/CH

Since February 2008 the Biozentrum of the University of Basel has been working with the Incoatec Microfocus Source IµS. Prof. Tilman Schirmer and his group at the Biozentrum use the high-performance combination of Incoatec Microfocus Source IµS and mardtb (Marresearch GmbH).

Tilman Schirmer:

"For one year now our IµS has been in use regularly for screening purposes, without us worrying about the X-ray source. The small protein crystals which are sensitive to X-rays are characterized under excellent conditions. This enables us to be much effective in choosing the correct sample for data collection at the synchrotron. In addition to that we use the IµS successfully for routine data collection. The IµS completely meets our expectations."

Field of research

Prof. Tilman Schirmer

Prof. Schirmer´s group carries out studies on the structural basis for solute translocation across the outer and the inner bacterial membrane. Their second focus is on proteins that are involved in signal transduction utilizing the cyclic dinucleotide c-diGMP, a recently discovered second messenger in prokaryotes.   Biozentrum, University of Basel, Research Group Prof. Tilman Schirmer

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